Ferintus® IV Injection/Infusion

Generic Name: Ferric Carboxymaltose
Strength: 500 mg elemental iron / 10 ml
Form: Sterile solution for IV injection or infusion
Manufacturer: Beiximco Pharmaceuticals Ltd.
Distributed by: NP Molecule

Description:

Ferintus® is an intravenous iron replacement therapy used for the treatment of iron deficiency anemia (IDA), particularly when oral iron is ineffective, poorly tolerated, or when there is a clinical need for rapid iron repletion.

Each vial (10 ml) contains Ferric Carboxymaltose INN equivalent to 500 mg elemental iron, provided in a sterile and pyrogen-free formulation. The product comes with necessary administration accessories including normal saline, infusion set, alcohol pad, and syringe.

Indications:

• Iron deficiency anemia in adults with chronic kidney disease

• IDA in patients with inflammatory bowel disease, postpartum anemia, heart failure, or those undergoing major surgery

• Patients who cannot tolerate oral iron or in whom oral iron is ineffective

Pharmacology:

Ferric carboxymaltose is a stable iron complex that allows controlled delivery of iron to the reticuloendothelial system. It enables rapid repletion of iron stores with fewer gastrointestinal side effects compared to oral iron.

Dosage & Administration:

• Administered via slow IV injection or infusion

• A single dose may range from 500 mg to 1,000 mg depending on the patient’s iron requirement

• Must be diluted with normal saline if given as an infusion

Note: Use only freshly prepared solution. Do not freeze.

Contraindications:

• Hypersensitivity to ferric carboxymaltose

• Anemia not caused by iron deficiency

• Iron overload or disturbances in iron utilization

Precautions & Warnings:

• Monitor for allergic reactions during and after administration

• Use caution in patients with liver disorders

• Avoid use in first trimester of pregnancy unless clearly necessary

Side Effects:

• Common: Injection site pain, dizziness, nausea, flushing

• Rare: Hypersensitivity or anaphylactic reactions

Storage:

• Store below 25°C

• Protect from moisture and light

• Keep out of reach of children

• Do not freeze

Therapeutic Class:

Parenteral Iron Preparations / Hematinics